Endocrinology & Reproductive Physiology SEQ

(1). Endocrinology & Reproductive Physiology
List the hormones involved in Ca2+ homeostasis and indicate the site of origin in each case.
A child presented with short stature and bowing of the legs. Explain the physiological basis of the child’s defect.
Describe the feedback control of thyroid secretion.
Define exopthalmos. Explain how exopthalmos is caused in a patient with hyperthyroidism.


(2). Describe

The effect of cortisol on bone.
Both males and females show increased gonadotrophin production after 50 years of age. Explain this statement.

(3). Explain the physiological basis of the following.
Although high serum prolactin levels are observed during the last trimester of pregnancy, lactation does not begin until after parturition.
Lactation is suppressed if the baby dies during the neonatal period.
Use of androgens to build muscle mass may result in male sterility.
A woman suspected to be subfertile was instructed to maintain a basal body temperature chart.


(4). Explain the physiological basis of the following.
A goiter maybe seen in hypothyroidism as well as in hyperthyroidism.
Moon face and poor wound healing are features of Cushing’s syndrome.
Large hands and feet and impaired glucose tolerance are features of Acromegaly.
A patient suffering from primary hyperaldosteronism has a lower renal plasma renin concentration than normal.
In some pregnant women, glycosuria occurs even when the blood sugar level is normal.

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