Which of following true or false regarding Na+ - K+ ATPase pump

• The energy is derived directly from breakdown of adenosine triphosphate (ATP )
• Or use  some other high-energy phosphate compound

• Na+ - K+ ATPase pum
• H, K ATPase in the gastric mucosa and the renal tubule
• Ca2+ATPase pump

• use energy orginaly created by primary active transport 

• Na+/glucose cotransporter (SGLT1) 
• Na+/phosphate cotransporter (NaPi) 
• Na+/I- symporter (NIS)

b. Pump 3Na + out and 2K+ ion into the cell


c. Na+ - K+ ATPase pump made up of an alpha  subunit with a molecular weight of approximately 100,000 and a beta  subunit with a molecular weight of approximately 55,000.


d. Maintain cellular volume 


e.

• Digoxin is a digitalis glycosides used to treat heart failure
• Oubain and digitalis glycoside block the Na, K ATPase in cardiomyocytes would result in an increased intracellular Na⁺ concentration.This result decrece  Na⁺  influx and Ca²⁺  efflux via the Na+-Ca2+ exchange antiport. Increase intracelluar Ca2+ level results increase strength of cardiac contraction . ^.

Labels: Excitable tissue, Excitable tissue MCQs, Excitable tissue SEQs, Physiology MCQ