Which of the following give rise to edema(T/F)
a) Increase capillary permeability
b) Increase in venous pressure
c) Decrease in plasma albumin
d) Increase tone of the pre capillary sphincters
e) Lymphatic obstruction
Answer
a.T
b.T
c.T
d.F
e.T
Discussion
What is Oedema
- Oedema is the accumulation of fluid in the interstitial space in abnormally large amount
Amount of fluid in the interstitial space depends on
- Capillary hydrostatic pressure (Pc)
- Interstitial hydrostatic pressure (Pi )
- Capillary colloid osmotic pressure (πc )
- Interstitial colloid osmotic pressure (πi )
- Capillary filtration coefficient ( k )
- Number of active capillaries
- Lymph flow
- Total ECF volume
Causes of oedema
Increased capillary hydrostatic pressure
- Arteriolr dilation
- Venular constriction
- Increase venous pressure
- Heart failure
- Incompetent valves
- Venous obstruction
- Increased total ECF volume
- Effect of gravity
Decreased capillary colloid osmotic pressure
Decreased plasma protein level (reduce albumin level)
- Nehrotic syndrome
- Liver disease
- Burns
- Malnutrition
- Accumulation of osmotically active substance in the interstitial space
Increased capillary permeability
- Inflammation
- Allergy
- Burns
- Poisoning
Inadequate lymph flow
- Filarisis
- Radical mastectomy
- Congenital
