1.Which is the gene defect in a patient with HNPCC

a. K- RAS

b. DCC

c. APC

d. P53

e. MSH 2 

2. APC gene mutated in
a. Familial adenomatous polyposis coli
b. Retinoblastoma
c.Ataxia telengectasia
d. Xeroderma pigmentosa
e.HNPCC

3. Which of following is not true
a. APC gene is a tumor supressor gene
b. APC protein form destructive complex for Beta ketanin
c. Mutation of one allele is enough to produce cancer
d. Mutated in Turcot syndrome
e.Mutated in Familial adenomatous polyposis

Answer

1.e MSH 2 

2. a. Familial adenomatous polyposis coli

3. C 

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